Publications

First & Corresponding Authors

* Co-first authorship # Corresponding authorship

2025

Blood-Based Single-Cell and Bulk RNA sequencing Identifies CAD-Driven CD4+T Cell Dysfunction in Aggressive Small Clear Cell Renal Carcinoma
Eunchae Kim*, Jee Soo Park*, Seol Song, Se-eun Han, Byungjin Hwang#, Won Sik Ham#
International Journal of Surgery. In revision.

2025

Paired snRNA-seq and scRNA-seq analysis of MASLD patients to identify early-stage markers for disease progression
Suebin Park*, Su-Hyeon Lee, Se-eun Han, Beom Kyung Kim#, Byungjin Hwang#
Hepatology Communications. 2025.

2025

Integrated single-cell multiomics analysis reveals the signatures of brain aging in mice
Se-eun Han*, Hyunjeong Kim*, Jieun Song, Dabin Song, Soyeon Cho, Changsoo Kim, Eosu Kim#, Byungjin Hwang#
Aging Cell. In revision.

2025

Integrative Single-Cell RNA-seq and TCR Repertoire Analysis Reveals Distinct Immunological Features of Acute Liver Allograft Rejection
Su-Hyeon Lee*, Deok-Gie Kim*, Yuri Cho, Eun-Ki Min, Jae Geun Lee, Myoung Soo Kim, Suebin Park, Byungjin Hwang#, Dong Jin Joo#
Genome Medicine. In revision.

2025

SCITO-seq2: Ultra-high-throughput single-cell transcriptome and epitope sequencing
Su-Hyeon Lee*, Bo-Yeong Jin*, Cho-Rong Lee, Doo Ri Kim, Areum Shin, Sung-Gyoo Park, Yae-Jean Kim, Seong Heon Kim, Murim Choi#, Byungjin Hwang#
Genome Biology. Accepted.

2024

Multiplexed multi-modal single cell technologies: From observation to perturbation analysis
Su-Hyeon Lee, Junha Park, Byungjin Hwang#
Molecules and Cells. 2024.

2024

T-Cell Dynamics Predicts Prognosis of Patients with Hepatocellular Carcinoma Receiving Atezolizumab Plus Bevacizumab
Hye Won Lee*, Suebin Park*, Hye Jung Park, Kyung Joo Cho, Do Young Kim#, Byungjin Hwang#, Jun Yong Park
Int. J. Mol. Sci.. 2024. DOI

2021

SCITO-seq: single-cell combinatorial indexed cytometry sequencing
Byungjin Hwang*, David S. Lee*, Whitney Tamaki, Yang Sun, Anton Ogorodnikov, George Hartoularos, Aidan Winters, Bertrand Yeung, Kristopher L. Nazor, Yun S. Song, Eric D. Chow, Matthew H. Spitzer, Chun Jimmie Ye#
Nature Methods. 2021. DOI

2019

Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements
Byungjin Hwang*, Wookjae Lee*, Soo-Young Yum*, Yujin Jeon, Namjin Cho, Goo Jang#, Duhee Bang#
Nature Communications. 2019. DOI

2019

Facilitated large-scale sequence validation platform using Tn5-tagmented cell lysates
Byungjin Hwang*, Sunghoon Heo*, Namjin Cho, Duhee Bang#
ACS Synthetic Biology. 2019. DOI

2018

Single-cell RNA sequencing technologies and bioinformatics pipelines
Byungjin Hwang*, Ji Hyun Lee#, Duhee Bang#
Experimental Molecular Medicine. 2018. (Citation >1,500) DOI

2017

Asymmetrical barcode adapter-assisted recovery of duplicate reads and error correction strategy to detect rare mutations in circulating tumor DNA
Jinwoo Ahn*, Byungjin Hwang*, Ha Young Kim*, Hoon Jang, Hwang-Phill Kim, Sae-Won Han, Tae-You Kim, Ji Hyun Lee#, Duhee Bang#
Scientific Reports. 2017. DOI

2016

Genomic Profile of Chronic Lymphocytic Leukemia in Korea Identified by Targeted Sequencing
Jung-Ah Kim*, Byungjin Hwang*, Si Nae Park, Sunghoon Huh, Kyongok Im, Sungbin Choi, Hye Yoon Chung, JooRyung Huh, Eul-Ju Seo, Je-Hwan Lee, Duhee Bang#, Dong Soon Lee#
PLOS ONE. 2016. DOI

2016

Toward a new paradigm of DNA writing using a massively parallel sequencing platform and degenerate oligonucleotide
Byungjin Hwang, Duhee Bang#
Scientific Reports. 2016. DOI

2015

De novo assembly and next-generation sequencing to analyze full-length gene variants from codon-barcoded libraries
Namjin Cho*, Byungjin Hwang*, Jung-Ki Yoon*, Sangun Park*, Joongoo Lee*, Han Na Seo, Jeewon Lee, Sunghoon Huh, Jinsoo Chung, Duhee Bang#
Nature Communications. 2015. DOI

Contributing Authors

2025

Exercise alters transcriptional profiles of senescence and gut barrier integrity in intestinal crypts of aging mice
Jeon H, Lee S, Kim Y, ... Han SE, Hwang B, Kim JW, Oh CM*, Fang S*
npj Aging. 2025.

2023

Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells
Connor A. Tsuchida, ... Byungjin Hwang, ... Chun Jimmie Ye#, Jennifer A. Doudna#
Cell. 2023.

2022

Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies
Daniel B. Goodman, ... Byungjin Hwang, David Lee, ... Kole T. Roybal#
Science Translational Medicine. 2022. DOI

2018

CRISPR-Cap: Multiplexed double-stranded DNA enrichment based on the CRISPR system
Lee J, Lim H, Jang H, Hwang B, Lee J, Cho J, Lee JH#, Bang D#
Nucleic Acids Research. 2018. DOI

2018

High-throughput construction of multiple cas9 gene variants assembly of high-depth tiled and sequence-verified oligonucleotides
Cho N, Seo HN, ... Hwang B, ... Kwon S#, Bang D#
Nucleic Acids Research. 2018. DOI

2017

The high frequency of the U2AF1 S34Y mutation and its association with isolated trisomy 8 in myelodysplastic syndrome in Asians
Kim SY, Kim K, Hwang B, ... Bang D#, Lee DS#
Leukemia Research. 2017. DOI

2017

Somatotroph-Specific Aip-Deficient Mice Display Pretumorigenic Alterations in Cell-Cycle Signaling
Gillam MP, Ku CR, Lee YJ, Kim J, Kim SH, Lee SJ, Hwang B, Koo JH, Kineman RD, Kiyokawa H, Lee EJ#
J. Endocr. Soc.. 2017. DOI

2015

Genetic Testing of Korean Familial Hypercholesterolemia Using Whole-Exome Sequencing
Han SM, Hwang B, ... Bang D#, Lee JH#, Lee SH#
PLOS ONE. 2015. DOI